REVIEW PAPER
Preterm delivery in multiple pregnancy
 
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Faculty of Health Sciences, Academy of Applied Medical and Social Sciences, Elbląg, Poland
 
 
Submission date: 2025-12-03
 
 
Final revision date: 2026-01-07
 
 
Acceptance date: 2026-01-09
 
 
Online publication date: 2026-01-12
 
 
Corresponding author
Małgorzata Świątkowska-Freund   

Akademia Medycznych i Społecznych Nauk Stosowanych w Elblągu, Poland
 
 
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Preterm delivery rates have been stable for many years. Improvement in diagnostic and treatment decreases the rates of spontaneous preterm delivery but increases frequency of iatrogenic prematurity.

Aim:
The aim of the review was to systematize knowledge about preterm delivery reasons in multiple pregnancies.

Material and methods:
Literature regarding preterm delivery in multiple pregnancy was analyzed.

Results and discussion:
Preterm delivery is more frequent in multiple pregnancies when compared to singleton gestations. There are many pathophysiological mechanisms of early shortening of uterine cervix, rupture of membranes and uterine contractions leading to delivery. Additional problem is related to multiple pregnancy complications, increasing the risk of both, spontaneous and iatrogenic, delivery.

Conclusions:
Multiple pregnancy is a risk factor of spontaneous and iatrogenic preterm delivery.
FUNDING
None declared.
CONFLICT OF INTEREST
None declared.
REFERENCES (11)
1.
Goldenberg R, Culhane J, Iams J, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371(9606):75–82. https://doi.org/10.1016/s0140-....
 
2.
Bręborowicz G, Malinowski W, eds. Multiple pregnancy [in Polish]. Warszawa: PZWL. 2022. https://doi.org/10.53270/2022.....
 
3.
Seetho S, Kongwattanakul K, Saksiriwuttho P, Thepsuthammarat K. Epidemiology and factors associated with preterm births in multiple pregnancy: a retrospective cohort study. BMC Pregnancy Childbirth. 2023;23(1):872. https://doi.org/10.1186/s12884....
 
4.
Wielgoś M, Bomba-Opoń D, Bręborowicz G, et al. Recommendations of the Polish Society of Gynecologists and Obstetricians regarding caesarean sections. Ginekol Pol. 2018;89(11):644–657. https://doi.org/10.5603/GP.a20....
 
5.
Kosiński P, Borowski D, Brawura-Biskupski-Samaha R, et al. Fetal therapy guidelines of the Polish Society of Gynecologists and Obstetricians – Fetal Therapy Section. Ginekol Pol. 2024;95(4):285–315. https://doi.org/10.5603/gpl.10....
 
6.
Bręborowicz G. Obstetrics [in Polish]. Warszawa: PZWL. 2020.
 
7.
Kosińska-Kaczyńska K, Torbe A, Kwiatkowski S, et al. The Polish Society of Gynecologists and Obstetricians guideline for the diagnostic assessment and management of multiple-gestation pregnancy complicated by fetal growth restriction. Ginekol Pol. 2022;93(3):256–263. https://doi.org/10.5603/GP.a20....
 
8.
Buskmiller C, Munoz J, Sanz Cortes M, Donepudi RV, Belfort MA, Nassr AA. Laser therapy versus expectant management for selective fetal growth restriction in monochorionic twins: A systematic review. Prenat Diagn. 2023;43(5):687–698. https://doi.org/10.1002/pd.634....
 
9.
Da Silva Rocha J, Guedes-Martins L, Cunha A. Twin Anemia-Polycythemia Sequence (TAPS): From Basic Research to Clinical Practice. Curr Vasc Pharmacol. 2023;21(2):91–105. https://doi.org/10.2174/157016....
 
10.
McDonnell BP, Martin A. Delayed interval delivery of preterm multiples: experience from a large specialized twin center. J Matern Fetal Neonatal Med. 2022;35(12):2227–2233. https://doi.org/10.1080/147670....
 
11.
De Frias CAS, Queirós ASPAF, Simões HTF. Delayed-Interval Delivery in Dichorionic Twin Pregnancies: A Case Report of 154 Latency Days. Rev Bras Ginecol Obstet. 2020;42(1):61–64. https://doi.org/10.1055/s-0040....
 
ISSN:1730-9980
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